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 Welcome to the VIB-UGent Center for Inflammation Research

Director: Prof. Dr. Bart LAMBRECHT

The VIB Center for Inflammation Research (IRC) is active within VIB and the Universities of Ghent, Brussels (VUB) and Hasselt.

Inflammation is the first response of the immune system to infection or tissue injury, leading to protection of the body against these insults. However, chronic inflammation forms the basis of several diseases such as asthma, rheumatoid arthritis, colitis, multiple sclerosis and even certain forms of cancer.

The IRC labs study the molecular mechanisms of inflammation. At the heart of this research is the investigation of molecular signaling pathways in inflammatory cells and structural cells of the skin, lung, gut and brain. We particularly focus on NF-κB, ER stress and cell death pathways and study how these are altered by disease. Research is multidisciplinary with molecular biologists, cell biologists, and bioinformaticians collaborating with clinicians.

It is the IRC's ambition to translate our basic research into innovative ways for diagnosis and therapy of human inflammatory diseases. To complement the mechanism-oriented research, IRC therefore actively supports R&D of innovative molecular biotechnological platforms. These tools offer new approaches to study the mechanisms of inflammation, and form the essential basis for novel diagnostics and therapeutics. The IRC has a track record of advanced translational biotechnology research, with several products now in clinical development. These products will soon benefit patients with Crohn's disease, allergies and lysosomal storage diseases.



VIB Center for Inflammation Research groups


Inna AFONINA

Team leader


Mathieu BERTRAND
Team leader


Rudi BEYAERT

Group leader


Wim DECLERCQ
Team leader


Dirk ELEWAUT
Group leader


Martin GUILLIAMS

Group leader


Hamida HAMMAD

Group leader


Esther HOSTE

Team leader


Sophie JANSSENS
Group leader


Markus KLEINEWIETFELD

Group leader


Bart LAMBRECHT

Director & Group leader


Damya LAOUI

Group leader


Debby LAUKENS

Team leader


Claude LIBERT

Group leader


Jonathan MAELFAIT

Team leader


Kodi RAVICHANDRAN

Group leader


Yvan SAEYS

Group leader


Savvas SAVVIDES

Group leader


Charlotte SCOTT

Group leader


Jens STAAL

Team leader


Peter VANDENABEELE

Group leader


Tom VANDEN BERGHE

Team leader


Roos VANDENBROUCKE

Group leader


Jo VAN GINDERACHTER
Group leader


Geert van LOO
Group leader


Lars VEREECKE

Team leader


Andy WULLAERT

Team leader


Ghent University groups


Geert BERX

Group leader


Vanessa VERMEIRSSEN

Group leader


Kris VLEMINCKX

Group leader


Helix sculpture

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