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IRC Ph.D. theses since 2000

 Pdf-versions of the theses (until Dec 2022) are available on the IRC intranet only (login required ). PhD theses from 2023 onwards can be found in the academic bibliography of UGent or requested by emailing the secretariat.

  1. Murgaski Aleksandar (20-December-2022 ; D. Laoui & J. Van Ginderachter)
    Understanding the effect and mechanisms of CD40 agonist therapy on tumour growth and dendritic cell vaccination strategies
  2. Xie Junhua (20-December-2022 ; R. Vandenbroucke, F. Haesebrouck & L. Van Hoecke)
    Studying the impact of the gastrointestinal bacteria on the brain, focusing on the blood-cerebrospinal fluid barrier and Alzheimer's disease
  3. Moon Sangphil (20-December-2022 ; M. Radwanska & S. Magez)
    Assessing impacts of experimental trypanosome infections on B cell memory
  4. Emmaneel Annelies (13-December-2022 ; Y. Saeys & S. Van Gassen)
    Improving diagnosis of primary immunodeficiencies using computational cytometry
  5. Tulkens Dieter (9-December-2022 ; K. Vleminckx & P. Van Vlierberghe)
    Uncovering novel cancer driver genes using CRISPR/Cas9 multiplexing in Xenopus tropicalis
  6. Heyndrickx Ines (25-November-2022 ; B. Lambrecht & H. Hammad)
    The role of protein crystals in type 2 immunity
  7. Iliaki Stella (26-October-2022 ; R. Beyaert & I. Afonina)
    Identification and functional characterization of CARD14 protein-protein interactions
  8. De Galan Cara (27-September-2022 ; D. Laukens & P. Hindryckx)
    New insights in the use of vedolizumab in inflammatory bowel disease
  9. Vetters Jessica (2-September-2022 ; S. Janssens)
    Novel pathways in NK cell biology
  10. Plehiers Nele (31-Augustus-2022 ; R. Vandenbroucke)
    Hijacking receptor-mediated transcytosis at the blood-cerebrospinal fluid barrier as delivery route for drugs to the brain
  11. Cappe Benjamin (7-July-2022 ; P. Vandenabeele & F. Riquet)
    Investigating the role of MLKL and EVs in cell-cell communication during necroptosis
  12. Pauwels Marie (28-June-2022 ; R. Vandenbroucke & L. Van Hoecke)
    Exploration of blood-cerebrospinal fluid barrier targeted extracellular vesicles as brain delivery strategy
  13. Jonckheere Sven (24-June-2022 ; G. Berx & S. Goossens)
    Therapeutic targeting of ZEB1-mediated EMT in metastatic colorectal cancer
  14. Remmerie Anneleen (13-June-2022 ; C. Scott & M. Guilliams)
    Understanding Hepatic Macrophage Phenotypes and Functions in Metabolic-Associated Fatty Liver Disease
  15. Kim Seo Woo (18-May-2022 ; R. Beyaert, J. Staal & A. Goossens)
    Unraveling the functional roles of endogenous phytohormones in mammals
  16. Holgado Muñoz Aurora (4-May-2022 ; R. Beyaert & I. Afonina)
    Targeting and regulation of interleukin-33 signalling in lung inflammation
  17. Van Coillie Samya (10-Dec-2021 ; P. Vandenabeele & T. Vanden Berghe)
    Therapeutic targeting of ferroptosis in experimental models of acute organ injury
  18. Delanghe Tom (10-Dec-2021 ; M.J. Bertrand & Y. Dondelinger)
    Unraveling the role of RIPK1 phosphorylation in TNF-mediated cell death and inflammation
  19. Vanderhaeghen Tineke (6-Dec-2021 ; C. Libert & R. Beyaert)
    The Effect of Hypoxia and Hypoxia Inducible Factors on the Glucocorticoid Receptor Function and their Role during Sepsis
  20. Srinivasan Sahana (3-Dec-2021 ; G. van Loo & M. Lamkanfi)
    Characterizing the role of microglial inflammation in neurodegeneration
  21. Oltean Teodora (30-Nov-2021 ; P. Vandenabeele, J. Maelfait & S. Adjemian Catani)
    Unraveling cell death modalities during influenza infection, vaccination, and cancer therapy
  22. Van Hove Lisette (19-Oct-2021 ; E. Hoste & G. van Loo)
    Unravelling molecular mechanisms mediating skin inflammation and tumour formation
  23. Fernandes Côrte-Real Beatriz (30-Sep-2021 ; M. Kleinewietfeld)
    The impact of high salt on Foxp3+ regulatory T cell metabolism and function
  24. Wiernicki Bartosz (27-Sep-2021 ; P. Vandenabeele, T. Vanden Berghe & K. Ravichandran)
    The role of lipid peroxidation in cell death and adaptive immune system regulation
  25. Vrancken Kurt (21-Sep-2021 ; P. Brouckaert & A. Blood)
    Plasma nitric oxide handling and its metabolism to endocrine S-nitrosothiol and nitrite: Role of ceruloplasmin and a novel function for postprandial triglyceride rich lipoproteins
  26. De Schutter Elke (8-Sep-2021 ; G. Van Camp, P. Vandenabeele & F. Riquet)
    Elucidation of the role of GSDME during apoptosis-driven secondary necrosis
  27. Percier-Lehebel Pauline (24-Aug-2021 ; W. Declercq, J. Grooten & O. Denis)
    Alternaria alternata and Aspergillus fumigatus mold species counteract experimental mycobacterial and allergic lung diseases through divergent innate immune mechanisms
  28. De Munck Steven (12-Jul-2021 ; S. Savvides)
    Structure and mechanism of cytokine mediated activation of ALK family receptor tyrosine kinases
  29. De Vos Tatjana (8-Jul-2021 ; S. Savvides)
    Structural basis for the activation and antagonism of the IL-9 signaling complex
  30. Loret Nele (08-Jun-2021 ; G. Berx, B. Lambrecht & P. Tummers)
    Cellular plasticity and heterogeneity in ovarian cancer progression and therapy resistance
  31. T'Jonck Wouter (28-Apr-2021 ; C. Scott)
    Notch-induced LXRα expression is essential for the maintenance of Kupffer cell identity
  32. Renson Thomas (15-Apr-2021 ; D. Elewaut, F. Van den Bosch & J. Dehoorne)
    Identifying pitfalls and opportunities of magnetic resonance imaging in spondyloarthritis
  33. Cloots Eva (12-Apr-2021 ; S. Janssens & S. Eyckerman)
    The ins and outs of IRE1B signaling: the role of IRE1B in mucosal homeostasis
  34. Vandewalle Jolien (24-Mar-2021 ; C. Libert & K. De Bosscher)
    The role of glucocorticoid resistance and TNFR1 signaling in sepsis
  35. Bosteels Cédric (26-Feb-2021 ; B. Lambrecht & H. Hammad)
    The role of DC subsets in respiratory viral infections and vaccination: a case of mistaken identity
  36. Vandendriessche Charysse (17-Dec-2020 ; R. Vandenbroucke & C. Van Cauwenberghe )
    Exploring the role of extracellular vesicles in Alzheimer’s and Parkinson’s disease
  37. Todorov Helena (16-Dec-2020 ; Y. Saeys & J. Marvel )
    Structure learning to unravel mechanisms of the immune system
  38. Dimitrakopoulou Dionysia (16-Oct-2020 ; K. Vleminckx & A. Willaert)
    CRISPR/Cas9 mediated modeling of TP53 and PTEN related malignancies in Xenopus tropicalis
  39. Gorlé Nina (19-Jun-2020 ; R. Vandenbroucke & F. Haesebrouck)
    Study of the importance of the choroid plexus in peripheral and brain inflammation
  40. Gilis Elisabeth (29-May-2020 ; D. Elewaut & S. Lambrecht)
    The role of MALT1 in rheumatic diseases
  41. Zuallaert Jasper (27-May-2020 ; W. De Neve, N. Callewaert & Y. Saeys)
    Automated learning of biologically relevant features from primary sequence using convolutional neural networks
  42. Priem Dario (22-Apr-2020 ; M. Bertrand)
    The ubiquitin-dependent regulation of the inflammatory response by A20 and MAGED1
  43. Van Wyngene Lise (19-Mar-2020 ; C. Libert & G. van Loo)
    The role of hepatic PPARa in sepsis and ZBTB32 in metabolic homeostasis
  44. Van Looveren Kelly (13-Mar-2020 ; C. Libert & K. De Bosscher)
    The glucocorticoid receptor in acute inflammation: new molecular insights and development of a new GR dimerization mutant
  45. Martens Arne (11-Feb-2020 ; G. van Loo)
    Mechanistic insights into the regulation of inflammatory pathology by A20
  46. Cannoodt Robrecht (16-Dec-2019 ; Y. Saeys & K. De Preter)
    Modelling single-cell dynamics with trajectories and gene regulatory networks
  47. Debeuf Nincy (13-Dec-2019 ; B. Lambrecht & S. Janssens)
    ORMDL3 in the regulation of sphingolipid synthesis and in the pathogenesis of allergic asthma
  48. Detry Sammy (9-Dec-2019 ; S. Savvides & Y. Bloch)
    Unraveling and targeting of molecular signaling mechanisms of IL-12 family, IL-18 and IL-33 cytokines using integrative structural biology
  49. Saelens Wouter (24-Oct-2019 ; Y. Saeys & B. Lambrecht)
    Developing and benchmarking methods for analysing transcriptomics data
  50. Brkic Marjana (27-Sep-2019 ; R. Vandenbroucke, S. Kanazir & C. Libert)
    Studies on structural and functional changes of mouse choroid plexus in the initiation of neuroinflammation
  51. Dubois Hanne (17-Sep-2019 ; A. Wullaert & M. Lamkanfi)
    Characterisation of innate immune responses associated with gastrointestinal norovirus infection
  52. Vanderkerken Matthias (16-Sep-2019 ; B. Lambrecht & T. Kerre)
    Molecular interactions controlling immune homeostasis in the marginal zone
  53. Bauwens Eva (3-Sep-2019 ; R. Vandenbroucke, F. Haesebrouck, A. Smet)
    Impact of gastric Helicobacter infections on the stomach-brain axis
  54. Martens Sofie (4-Jul-2019 ; P. Vandenabeele, V. Goossens, N. Takahashi)
    Necroptotic proteins in diseases: targeting RIP kinases in inflammatory disorders and exploring the role of MLKL in melanoma development
  55. Sabaghian Ehsan (1-Jul-2019 ; Y. van de Peer & Y. Saeys)
    Unravelling gene functions in Arabidopsis thaliana by means of network biology and machine learning
  56. Van Nuffel Elien (27-Jun-2019 ; R. Beyaert & I. Afonina)
    CARD14/MALT1 signaling in skin homeostasis and disease
  57. Naert Thomas (21-Jun-2019 ; K. Vleminckx)
    CRISPR/Cas9-mediated cancer modeling and identification of cancer cell vulnerabilities in Xenopus tropicalis
  58. Bolli Evangelia (19-Jun-2019 ; J. Van Ginderachter)
    Nanobody-mediated targeting of tumor-associated macrophages for cancer therapy
  59. Cambré Isabelle (4-Jun-2019 ; D. Elewaut & S. Lambrecht)
    Mechanical strain and its implications for mouse and human rheumatic diseases
  60. De Smedt Eva (23-May-2019 ; G. Berx)
    ZEB1 as 'jack-of-all-trades' in breast cancer progression
  61. Roels Joris (3-May-2019 ; Y. Saeys & W. Philips)
    Automated Segmentation of 3D Electron Microscopy Images
  62. Voet Sofie (15-Mar-2019 ; G. van Loo)
    Study of inflammatory signaling and microglia activation in central nervous system pathology
  63. Lork Marie Therese (8-Mar-2019 ; R. Beyaert, J. Staal)
    Molecular regulation of T cell receptor signaling
  64. Vandersarren Lana (27-Feb-2019 ; S. Janssens, B. Lambrecht)
    ER stress and T cell biology: IRE1 signaling and TAOK3 function
  65. Haspeslagh Eline (14-Feb-2019 ; H. Hammad, B. Lambrecht)
    Pulmonary immunomodulation of house dust mite-induced allergic asthma
  66. Pannecoucke Erwin (14-Feb-2019 ; S. Savvides)
    An integrative approach towards unraveling the activation of oncogenic FLT3
  67. Pauwels Anne-Marie (7-Jan-2019 ; R. Beyaert, Hoffmann E.)
    Impact of TLR4 engagement on the phagosomal proteome in dendritic cells and consequences for antigen degradation and presentation
  68. Mamantopoulos Michail (19-Dec-2018 ; A. Wullaert, M. Lamkanfi)
    Inflammasomes in intestinal host-microbe interactions
  69. Timmermans Steven (11-Dec-2018 ; C. Libert, Y. Saeys)
    Identifying and classifying protein coding gene polymorphisms between laboratory mouse strains and investigating glucocorticoid actions in sepsis models
  70. Souffriau Jolien (7-Dec-2018 ; C. Libert)
    Targeting TNF-induced acute inflammation by making use of SEDIGRAM or zinc
  71. Fulara Aleksandra (7-Dec-2018 ; S. Savvides)
    Study of the GspLM complex, an inner membrane component of the type II secretion system from Pseudomonas aeruginosa
  72. Vluymans Sarah (29-June-2018 ; Y. Saeys, C. Cornelis)
    Dealing with Imbalanced and Weakly Labelled Data in Machine Learning using Fuzzy and Rough Set Methods
  73. Godar Marie (29-June-2018 ; B. Lambrecht, C. Blanchetot)
    Development of Novel Multifunctional Antibodies to Treat Asthma
  74. Saavedra Pedro H. V. (26-June-2018 ; A. Wullaert, M. Lamkanfi)
    Mechanism and functions of the cytosolic receptor Pyrin
  75. Moraes de Vasconcelos Nathalia (26-June-2018 ; A. Wullaert, M. Lamkanfi)
    Cell death signaling at the crossroads of inflammasome activation
  76. Slowicka Karolina (21-June-2018 ; G. van Loo, L. Vereecke)
    Study of intestinal homeostasis and pathology through mouse gene targeting
  77. Soen Bieke (30-May-2018 ; G. Berx)
    Zeb1 and Zeb2: master regulators of mononuclear phagocyte development and homeostasis
  78. De Keuckelaere Evi (22-May-2018 ; F. Van Roy, G. Berx)
    The role of Nanos3 in tumor progression
  79. Kip Elodie (9-May-2018 ; R. Beyaert, S. De Gucht)
    Impact of the paracaspase MALT1 on rabies virus-induced neuroinflammation and disease
  80. Sundararaman Srividhya (26-Apr-2018 ; F. Van Roy, K. Vleminckx)
    Cadherin repertoires in lower metazoans - Trichoplax adhaerens and Nematostella vectensis
  81. Bloch Yehudi (16-Apr-2018 ; S. Savvides, K. Verstraete)
    Structure, mechanism, and antagonism of the pro-inflammatory receptor complex mediated by interleukin-23
  82. Carron Philippe (30-Mar-2018 ; D. Elewaut, F. Van den Bosch)
    New Imaging modalities and treatment strategies in Spondyloarthritis
  83. Delvaeye Tinneke (9-Mar-2018 ; P. Vandenabeele, D. Krysko, L. Leybaert)
    The pathological role of Cx43 and MLKL in TNF-induced Systemic Inflammatory Response Syndrome
  84. Noelanders Rivka (1-Mar-2018 ; K. Vleminckx)
    Wnt/beta-catenin signaling in the Xenopus hindbrain: development and cancer
  85. Tanghe Giel (23-Feb-2018 ; W. Declercq)
    Mechanistic insights into the regulation of RIPK4 and its function in skin homeostasis and pathology
  86. Berings Margot (21-Feb-2018 ; M. Dullaers, P. Gevaert, B. Lambrecht)
    House dust mite allergic rhinitis: A novel take on diagnosis and treatment
  87. Varkas Gaëlle (20-Feb-2018 ; D. Elewaut, F. Van den Bosch)
    Axial spondyloarthritis: New insights in diagnosis and patient stratification
  88. D'hondt Sanne (15-Dec-2017 ; F. Malfait, S. Janssens & M. Bertrand)
    Type III collagen, a major fibrillar collagen with major issues
  89. Dendoncker Karen (13-Oct-2017 ; C. Libert)
    Elucidating the mechanism behind TNF-induced glucocorticoid resistance and strategies to overcome this resistance
  90. Steeland Sophie (5-Oct-2017 ; C. Libert & R. Vandenbroucke)
    Therapeutic targeting of inflammatory mediators in sepsis and neurodegenerative diseases
  91. Favreau Mérédis (4-Oct-2017 ; D. Elewaut, K. Venken, E. Menu & K. Vanderkerken)
    Immune therapy in multiple myeloma: Can iNKT cells be targeted?
  92. Abels Chloé (26-Sep-2017 ; J. Van Ginderachter, P. De Baetselier & A. Beschin)
    Unravelling the role of liver associated myeloid cells in sterile inflammation and infection
  93. De Wilde Katelijne (20-Sep-2017 ; D. Elewaut & S. Lambrecht)
    Novel myeloid regulators of rheumatic diseases
  94. Bogaert Delfien (4-Sep-2017 ; M. Dullaers, F. Haerynck & E. De Baere)
    Molecular diagnosis of Common Variable Immunodeficiency and related antibody disorders: an integrated immunological and genetic approach
  95. Van der Borght Katrien (7-Jul-2017 ; B. Lambrecht)
    Cardiac dendritic cells activate autoreactive T cells in the healthy and diseased heart
  96. Deckers Julie (5-Jul-2017 ; H. Hammad & K. De Bosscher)
    The skin as a central player in house dust mite allergy
  97. Aaes Tania Love (5-Jul-2017 ; P. Vandenabeele & D. Krysko)
    The impact of cell death modalities on the immunogenicity of cancer cells
  98. Vandamme Niels (26-Jun-2017 ; G. Berx)
    ZEB1 and ZEB2 dictate melanocyte homeostasis and melanoma phenotype switching
  99. Ruyssinck Joerie (19-Jun-2017 ; Y. Saeys & T. Dhaene)
    Machine Learning for Biological Network Inference
  100. Krols Michiel (13-Jun-2017 ; S. Janssens & V. Timmerman)
    Mutations in Atlastin-3: implications for ER membrane fusion and crosstalk with mitochondria
  101. Le Cann Fabienne (2-Jun-2017 ; P. Vandenabeele)
    Characterization of new necroptosis innhibitors targeting RIPK1
  102. Udhayakumar Vimal Kumar (24-May-2017 ; J. Grooten & S. De Koker)
    Development and validation of synthetic-virus like vaccines
  103. Van Gassen Sofie (23-May-2017 ; Y. Saeys & T. Dhaene)
    Development of Machine learning techniques for flow cytometry data
  104. Govindarajan Srinath (16-May-2017 ; D. Elewaut & M. Drennan)
    Mechanistic insights into the regulation of iNKT development and cytokine production
  105. Schuijs Martijn (14-Apr-2017 ; H. Hammad and B. Lambrecht)
    The Pathogenesis of House Dust Mite-driven Asthma: From Barn to Bedside
  106. Ladik Maria (4-Apr-2017 ; P. Vandenabeele)
    Development of biosensing systems to monitor necroptosis
  107. Van Nieuwenhuysen Tom (31-Mar-2017 ; K. Vleminckx)
    Modeling human disease in Xenopus tropicalis using programmable nucleases
  108. Urwyler-Rösselet Corinne (17-Mar-2017 ; W. Declercq & P. Vandenabeele)
    Study of the functions of RIPK4 in epidermal development and signal transduction
  109. Balusu Sriram (15-Mar-2017 ; R. Vandenbroucke & C. Libert & K. Gevaert)
    Novel insights into the choroid plexus response to systemic inflammation and Alzheimer's disease
  110. Vermeulen Ilke (3-Mar-2017 ; J. Grooten)
    Tuberculosis: how different synthetic analogues of pathogen associated mycolates affect lipid homeostasis of murine host macrophages
  111. Catrysse Leen (24-Feb-2017 ; G. van Loo & R. Beyaert)
    Diabetes and inflammation, how A20 regulates tissue homeostasis in metabolic tissues
  112. Sichien Dorine (24-Feb-2017 ; B. Lambrecht & M. Guilliams)
    Differential requirement for IRF8 in the development and function of monocytes and dendritic cells
  113. Tavernier Simon (31-Jan-2017 ; B. Lambrecht & S. Janssens)
    Dendritic cells under stress: on the role of the unfolded protein response and hypoxia signalling
  114. Cypers Heleen (23-Jan-2017 ; D. Elewaut)
    The role of intestinal inflammation in initiation, monitoring and outcome of spondyloarthritis
  115. De Beuckelaer Ans (23-Dec-2016 ;J. Grooten)
    mRNA-based vaccines to elicit CD8 T cell immunity
  116. Borghi Alice (22-Dec-2016 ;R. Beyaert)
    New insight into the ubiquitin-mediated regulation of TNFR2 signaling
  117. Hassannia Behrouz (22-Dec-2016 ;P. Vandenabeele)
    Ferroptosis: triggers, inhibitors and therapeutic potential in neuroblastoma
  118. Van Putte Wouter (19-Dec-2016 ;S. Savvides)
    The type II secretion system and membrane vesiculation: bacterial secretion systems as a target for anti-virulence drug development
  119. Meloni Laura (8-Dec-2016 ;R. Beyaert)
    Molecular mechanisms of mechanotransdcution and osteoclastogenesis in arthritis
  120. Gül Ismail Sahin (6-Dec-2016 ;F. Van Roy)
    Molecular evolution of the armadillo repeat superfamily and characterization of representative members in key model organisms
  121. Demeestere Delphine (2-Dec-2016 ;C. Libert & R. Vandenbroucke)
    A study of inflammatory mechanisms involved in systemic inflammation and brain trauma
  122. Ballegeer Marlies (2-Dec-2016 ;C. Libert & R. Vandenbroucke)
    Study of the role and regulation of Glucocorticoid induced leucine zipper (GILZ) and GR dimers in acute inflammation
  123. Neyt Katrijn (21-Oct-2016 ;B. Lambrecht & M. Guilliams)
    Pulmonary immune responses against influenza A virus infection
  124. Jimenez Fernandez Daniel (22-Sep-2016 ;L. Lamkanfi & K. Gevaert)
    Functional characterization of inflammatory caspases
  125. Billi Eleonora (22-Sep-2016 ; F. Van Roy & J. Tavernier)
    Identification and functional analysis of molecular interaction partners of δ-protocadherin family members with putative roles in cancer
  126. Sips Magdalena (31-Aug-2016 ; P. Brouckaert)
    Harnessing innate immunity to prevent and control HIV infection
  127. Demeyer Annelies (28-Jun-2016 ; R. Beyaert)
    Functional characterization of the paracaspase MALT1 in T cells
  128. Grootjans Sasker (15-Apr-2016 ; P. Vandenabeele)
    Identification of potential RIPK1 substrates during Necroptosis
  129. Aguileta Miguel (15-Apr-2016 ; M. Bertrand & P. Vandenabeele)
    Characterization of new proteins involved in apoptosis regulation
  130. Juchtmans Nele (22-Mar-2016 ; D. Elewaut)
    The role of stress related proteins in osteoarthritis
  131. Félix Jan (7-Jan-2016 ; S. Savvides)
    Structural Principles of binding duality in cognate and viral cytokine receptors
  132. Petta Ioanna (4-Dec-2015 ; C. Libert & J. Tavernier)
    Identification of striatin-3 and ZBTB32 as two novel modulators of glucocorticoid receptor activity
  133. Sipieter François (3-Dec-2015 ; F. Riquet, P. Vandenabeele, K. Cailliau-Maggio & L. Héliot)
    Development and validation of kinase activity reporters for the dynamical study of cell response modalities by microscopy ~ Role of the kinase MAPK/ERK in necroptosis.
  134. Deng Lei (3-Dec-2015 ; X. Saelens)
    Targeted prokaryotic delivery of a conserved influenza A virus epitope for oral vaccination
  135. Santens Francis (25-Sep-2015 ; N. Callewaert)
    Engineering of protein production systems to drastically reduce glycan heterogeneity of biopharmaceuticals
  136. Claes Katrien (11-Sep-2015 ; N. Callewaert)
    Development of modular engineering tools for membrane protein expression in yeast
  137. Dondelinger Yves (3-Jul-2015 ; P. Vandenabeele & M. Bertrand)
    Unraveling the molecular mechanisms of RIPK1-mediated cell death
  138. Vandewalle Kristof (19-Jun-2015 ; N. Callewaert)
    Building genome-wide mutant resources in slow-growing mycobacteria
  139. De Visscher Charlotte (20-Feb-2015 ; N. Callewaert)
    Engineering of the production of mannose-6-phosphate-modified lysosomal enzymes by the yeast Pichia pastoris
  140. Elton Lynn (19-Dec-2014 ; R. Beyaert)
    Identification and functional characterization of novel MALT1 substrates
  141. Smet Muriel (18-Dec-2014 ; J. Grooten)
    Cholesterol-sensing liver X receptors and mycolic acid bio-lipids at the crossroads of lipid metabolism and inflammation
  142. Mueller Christina (16-Dec-2014 ; R. Beyaert)
    Molecular and functional characterization of interleukin-33 signaling
  143. Volckaert Thomas (8-Dec-2014 ; R. Beyaert)
    Epithelial-mesenchymal crosstalk during lung development and regeneration
  144. Grine Lynda(25-Nov-2014 ; C. Libert)
    Study of the role of type I Interferons in TNF-mediated inflammation.
  145. Tyberghein Koen (30-Sep-2014 ; F. Van Roy)
    Alpha-catenins: protein replacement as a strategy against cancer invasion and metastasis?
  146. Ydens Elke (24-Apr-2014 ; S. Janssens & V. Timmerman)
    Activation of the innate immune response during peripheral nerve degeneration: from pattern recognition receptors to immune effector cells
  147. Broos Stefan (24-Jan-2014 ; F. Van Roy & P. De Bleser)
    Developing algorithms for the in silico identification of transcription factor binding sites
  148. Vandendriessche Benjamin (13-dec-2013 ; P. Brouckaert & A. Cauwels)
    Complex dynamics in systemic inflammation: quantification of coupling and targeting of the nitric oxide-soluble guanylate cyclase axis
  149. Pollard Charlotte (6-dec-2013 ; J. Grooten & S. De Koker)
    Evaluation of CD8+ T cell responses upon mRNA vaccination and the implication of type I IFN signaling
  150. Puimège Leen (29-nov-2013 ; C. Libert)
    A molecular genetic analysis of TNFR1 regulation in SPRET/EI and generation of new TNFR1 inhibitory tools
  151. Vandevyver Sofie (22-nov-2013 ; C. Libert)
    Study of the molecular mechanisms of glucocorticoid receptor function and resistance in TNF-induced toxicity
  152. Plantinga Maud (16-Oct-2013 ; Bart Lambrecht)
    The role of dendritic cell subsets in allergic sensitization
  153. Ayiseh Rene B. (19-Sep-2013 ; P. Vandenabeele)
    Role of cell death and caspases in intestinal inflammation
  154. Kaczmarek Agnieszka (4-Jul-2013 ; P. Vandenabeele)
    Sensing of apoptotic and necroptotic cell death by the innate immune system
  155. Willart Monique (27-Jun-2013 ; B. Lambrecht)
    Immune activation at the lung epithelial barrier
  156. McGuire Conor (31-May-2013 ; G. van Loo & R. Beyaert)
    The study of signaling pathways controlling central nervous system inflammation and pathology
  157. De Baets Sarah (10-Apr-2013 ; X. Saelens)
    Novel vaccination strategies against human repiratory syncytial virus
  158. Pringels Sarah (17-Apr-2013 ; J. Grooten)
    Screening of the Vascular Endothelial Growth Factor family in human colon cancer
  159. Cardoso Francisco Miguel Lopez (28-Feb-2013 ; X. Saelens)
    Antiviral activity of camelid single domain antibodies targeting the neuraminidase of H5N1 Influenza virus
  160. De Groote Philippe (21-dec-2012 ; W. Declercq)
    Study of RIPK4 function in skin homeostatsis and disease
  161. Devos Michael (21-dec-2012 ; W. Declercq)
    Study on the role of delatNp63alpha and caspase-14 in skin homeostasis and pathology
  162. Kahr Irene (20-dec-2012 ; F. Van Roy)
    Functional analysis of the candidate tumor suppressor protein protocadherin-10
  163. Verhelst Judith (19-dec-2012 ; X. Saelens)
    Unraveling the antiviral mechanism of mouse Mx1 directed against influenza A
  164. Janssens Sylvie (19-Oct-2012 ; K. Vleminckx)
    Identification of novel target genes of the Wnt/β-catenin pathway during Xenopus development and analysis of their epigenetic regulation
  165. Haenebalcke Lieven (5-Oct-2012 ; J. Haigh)
    Generation and use of novel ROSA26-based ESC/iPSC technologies to study cellular reprogramming and gene function during lineage-directed differentiation
  166. Naessens Thomas (6-Jul-2012 ; J. Grooten)
    Functional dynamics of resident alveolar macrophages in a mouse model of allergic asthma
  167. Vander Beken Seppe (6-Jul-2012 ; J. Grooten)
    Mycobacterium tuberculosis bio-lipid mycolic acid and mammalian cholesterol-sensor liver X-receptor in airway immunity
  168. Farhang Ghahremani Morvarid (5-Jul-2012 ; J. Haigh)
    Molecular and genetic interplay between p53 and VEGF in tumour angiogenesis
  169. Meuris Leander (2-Jul-2012 ; N. Callewaert)
    GlycoDelete: a new glycoengineering concept for protein production in mammalian cells
  170. Nittner David (8-Jun-2012 ; J.C. Marine)
    Role of the microRNA pathway in retinoblastoma
  171. Guerfal Mouna (8-May-2012 ; N. Callewaert)
    Yeast secretory system engineering for enhanced membrane protein expression
  172. Roose Kenny (26-Jan-2012 ; X. Saelens)
    Design and validation of novel broad influenza B vaccine
  173. Andries Vanessa (26-Jan-2012 ; F. Van Roy)
    Functional analysis of the NBPF1 gene in cancer
  174. Bekaert Tine (20-Jan-2012 ; R. Beyaert)
    Functional characterization of the paracaspase MALT1
  175. Gembarska Agnieszka (19-Jan-2012 ; J.C. Marine)
    MDMX is a key therapeutic target in skin melanoma
  176. Schotsaert Michael (16-Dec-2011 ; X. Saelens)
    Modulation of humoral and cellular immunity to influenza by vaccination
  177. Zwolinska Aleksandra (15-Dec-2011 ; J.C. Marine)
    Study of three putative nuclear modulators of the p53 pathway
  178. Fransen Mathias (9-Dec-2011 ; K. Vleminckx)
    Exploring the role of caspases and RIPK4 during Xenopus development
  179. Van Hauwermeiren Filip (25-Nov-2011 ; C. Libert)
    New strategies to prevent TNF-induced toxicity in TNF/IFNgamma-based anti-tumor models
  180. Gheldof Alexander (21-Oct-2011 ; G. Berx)
    Functional analysis of the EMT inducing transcription factor ZEB1 during malignant carcinoma progression
  181. Duprez Linde (14-Oct-2011 ; P. Vandenabeele)
    Role of RIP1 in TNF-induced cell death in vitro and in vivo
  182. Tatari Marianthi (26-Sep-2011 ; G. Berx)
    In vivo analysis of the role of ZEB2 in epithelial homeostasis and tumor progression
  183. Pinheiro Iris (8-Jul-2011; C. Libert)
    Molecular cloning of the X-chromosome located LPS-resistance gene of SPRET/Ei mice
  184. Maelfait Jonathan (8-Jul-2011; R. Beyaert)
    Signaling in antiviral immunity and its regulation by the ubiquitin-editing protein A20
  185. Lambertz Irina (6-Jul-2011; J.C. Marine)
    MicroRNA control of cancer development
  186. Vanlangenakker Nele (1-Jul-2011; P. Vandenabeele)
    Unraveling TNF-induced necrotic signaling pathways using RNA interference and live-cell imaging
  187. Quimbaya Mauricio (23-Jun-2011; L. De Veylder & G. Berx)
    Identification of novel conserved cell cycle genes through data integration and comparative genomics between plants and humans
  188. Verhelst Kelly (17-Jun-2011; R. Beyaert)
    Molecular analysis of the ubiquitin-editing protein A20
  189. Vereecke Lars (27-May-2011; R. Beyaert)
    Controlling inflammation and cell death at the intestinal epithelial interface and beyond: Lessons from conditional 120 knockout mice
  190. De Pourcq Karen (27-May-2011; N. Callewaert)
    Glycosylation engineering in the yeast Yarrowia lipolytica: creating an expression system to produce complete homogeneous glycoproteins
  191. Wirawan Ellen (8-Apr-2011; P. Vandenabeele)
    Molecular interplay between autophagy and apoptosis through caspase-mediated cleavage of Beclin-1
  192. Kersse Kristof (8-Apr-2011; P. Vandenabeele)
    Inflammasome modulation and NF-kB activation by caspase-1-related CARD domains
  193. Dejonckheere Eline (1-Apr-2011; C. Libert)
    The role of matrix metalloproteinase 8 in TLR4-mediated acute systemic inflammation
  194. Pieters Tim (25-Feb-2011; F. Van Roy)
    Functional analysis of mice harboring a knock-out or knock-in of the alternatively spliced exon C of p120ctn
  195. Hooghe Bart (25-Feb-2011; F. Van Roy)
    In silico approaches to studying transcriptional gene regulation: prediction of transcription factor binding sites and applications thereof
  196. De Clercq Sarah (5-Jul-2010; J.-C. Marine)
    Study of the physiological and oncogenic properties of Mdm2 and Mdm4
  197. Van Bogaert Tom (1-Jul-2010; C. Libert)
    Study of the molecular mechanism of glucucorticoid resistance in tumor necrosis factor-induced systemic inflammation
  198. Galle Marlies (1-Jul-2010; R. Beyaert)
    Modulation of macrophage immune responses by the Pseudomonas aeruginosa type three secretion system
  199. Hoste Esther (24-Jun-2010; W. Declercq & P. Vandenabeele)
    Study of the role of caspase-14 in epidermal cornification
  200. Lefever Tine (3-Jun-2010; F. Van Roy)
    Analysis of N-WASP function in keratinocytes in vivo
  201. Vanderschaeghe Dieter (1-Jun-2010; J. De Langhe & N. Callewaert)
    GlycoHepatoTest: validation and analytical technology development for implementation on microfluidics analyzer
  202. Dejager Lien (30-Apr-2010; C. Libert)
    Molecular and genetic analysis of the resistance of the mouse strain SPRET/Ei to endotoxemia and Gram-negative sepsis
  203. Houthuys Erica (2-Apr-2010; P. Brouckaert)
    Transcriptome analysis of monocytes and macrophages in mycobacterial infection and chronic kidney disease
  204. Thoonen Robrecht (26-Feb-2010; P. Brouckaert)
    Generation and characterization of apo-soluble Guanylate Cyclase mice
  205. Vanhooren Valerie (27-Nov-2009; C. Libert)
    Glycomics of mammalian aging
  206. Crabbe Ellen (20-Nov-2009; K. Vleminckx)
    Identification and functional characterization of novel N-cadherin interacting proteins
  207. Willemarck Nicolas (20-Nov-2009; K. Vleminckx)
    Het Xenopus embryo als experimenteel platform voor de exploratie van nieuwe functies voor caspasen en tumorgeassocieerde de novo lipogenese
  208. Schoonooghe Steve (19-Oct-2009; J. Grooten)
    Multivalent and cross-reactive bispecific bibodies and tribodies for enhanced MUC1 tumour targeting
  209. Vanlaere Ineke (24-Sep-2009; C. Libert)
    Role of MMP-7 and IL-17A in acute systemic inflammation
  210. Demon Dieter (22-Jun-2009; P. Vandenabeele)
    Caspase-7: protease specificity activation and construction of a conditional knockout
  211. Tran Hong Thi (19-Jun-2009; K. Vleminckx)
    Development and use of novel transgenic lines to study Wnt signaling in the Xenopus embryo
  212. Huang Lieven (7-Jan-2009; R. Beyaert/P. De Baetselier)
    Characterization of EGF receptor targeting Nanobodies and ABIN for the treatment of EGF receptor-dependent tumours
  213. De Koker Stefaan (28-Oct-2008; N. Mertens/J. Grooten)
    Polyelectrolyte microcapsules for antibody delivery
  214. Huyghe Leander (10-Oct-2008; P. Brouckaert)
    Study of molecular and immunological factors that determine the sensitivity to the antitumor effect of Tumor Necrosis factor
  215. Bogaert Pieter (27-Mar-2008; J. Grooten)
    Transcriptome profiling of macrophage activation and inflammatory mediator expression in experimental mouse models of allergic pulmonary inflammation
  216. Jacobs Pieter (29-Feb-2008; N. Callewaert)
    Glycosylation and cell surface engineering in Pichia pastoris
  217. Vandewalle Cindy (28-Feb-2008; G.Berx & F. Van Roy)
    The role and mechanisms of SIP1 in the dedifferentiation of epithelial cancers
  218. Beekman Chantal - (21-Jan-2008; J.-C. Marine & F. Van Roy)
    A study of three putative players in the p53 pathway: Nucleostemin, Ptprv and TCTP
  219. Verschuere Veerle - (20-Dec-2007; K. Vleminckx)
    Analysis of the role of the p120 catenin subfamily in cell adhesion and cell migration during the early development of Xenopus laevis
  220. Loos Michaela - (7-Dec-2007; E. Remaut)
    Modulation of dendritic cell function through delivery of effector proteins by genetically modified Lactococcus lactis
  221. Coornaert Beatrice - (30-Nov-2007; R. Beyaert)
    MALT1 paracaspase-mediated regulation of the NF-kappaB inhibitory protein A20 in antigen receptor signaling
  222. Van Huynegem Karolien - (23-Nov-2007; E. Remaut)
    Genetically modified Lactococcus lactis as a tool in the prevention and healing of chemotherapy-induced intestinal mucositis
  223. Ovaere Petra - (5-Oct-2007; P. Vandenabeele)
    Identification of a Caspase-14 activating protease in murine skin extracts
  224. Verstrepen Lynn - (5-Oct-2007; R. Beyaert)
    Functional characterization of ABIN-3 and TAX1BP1 as negative regulators of NF-kappaB signaling
  225. Vande Walle Lieselotte - (28-Sep-2007; P. Vandenabeele)
    Role of the mitohondrial serine protease HtrA2/Omi in apoptosis
  226. Sips Patrick  (6-Jul-2007; P. Brouckaert)
    Functional analysis of soluble guanylate cyclase isoforms using mouse transgenics: cardiovascular effects of targeted mutagenesis of the alpha 1 subunit
  227. Vercammen Elisabeth  (22-Jun-2007; R. Beyaert)
    The secret life of Interleukin-1beta: molecular mechanisms involved in its production and biological activities
  228. Goethals An  (11-May-2007; P. Brouckaert)
    Studie in muismodellen van de mechanismen verantwoordelijk voor het antitumoraal effect van Tumor Necrosis Factor
  229. Van Lint Philippe  (20-apr-07, 16h30; C. Libert)
    The role of matrix metalloproteinases in specific inflammatory disorders
  230. Van Roy Maarten  (20-apr-07, 14h00;  C. Libert)
    New strategies to improve the safety and efficacy of a TNF/IFNgamma-based antitumor therapy
  231. Schepens Bert  (6-Oct-2006; R. Beyaert)
    The great escape: how Internal Ribosome Entry Sites can initiate translation of crucial mRNAs during hypoxia and mitosis
  232. De Smet Kris  (29-Sep-2006; R. Contreras)
    Studie van het celdoodproces in Candida albicans
  233. Schauvliege Reinout  (29-Sep-2006; R. Beyaert)
    Molecular mechanisms of LPS-induced pro-inflammatory signalling
  234. Delvaye Mieke  (28-Sep-2006; F. Van Roy & K. Vleminckx)
    Analysis of the morphogenetic role of known and novel cadherin-interacting proteins in Xenopus laevis
  235. Festjens Nele  (7-Jul-2006; P. Vandenabeele & X. Saelens)
    Characterization of molecular mechanisms associated with and involved in necrotic cell death
  236. Krysko Dmitri  (5-Jul-2006; K. D'Herde & P. Vandenabeele)
    Cell death: Initiation, propagation and clearance
  237. Laukens Debby  (29-Jun-2006; E. Remaut & P. Rottiers)
    Transcriptome profiling and genetic analysis to identify and characterize susceptibility genes for Crohn's disease
  238. Wullaert Andy  (5-May-2006; R. Beyaert)
    Effect of ABINs on intracellular signaling pathways involved in TNF-mediated liver injury
  239. Mahieu Tina  (31-Mrch-2006; C. Libert)
    A molecular analysis of the LPS resistance of the mouse species /Mus spretus
  240. Bultinck Jennyfer  (16-Mrch-06; P. Brouckaert)
    (Sub)cellular expression patterns and pathophysiological significance of INOS in inflammatory shock
  241. Goossens Steven  (24-Feb-06; F. Van Roy)
    Functional analysis of mouse alpha T-catenin
  242. Heirman Ingeborg  (1-Feb-06; J. Grooten)
    The tumor cell oxidative status and its interaction with eicosanoid synthesis in the control of tumor growth and malignant progression
  243. Vandepoele Karl  (22-Dec-2005; F. Van Roy)
    Genomic characterization and functional analysis of the novel NBPF gene family
  244. Termont Sofie  (16-Dec-2005; E. Remaut & P. Rottiers) 
    Optimization of Lactococcus lactis mediated mucosal delivery of cytokines
  245. Ryckaert Stefan  (9-Dec-2005; R. Contreras)
    Ontwikkeling van nieuwe toepassingen voor gist oppervlakte-expressie
  246. Soubry Adelheid  (6-Dec-2005; F. Van Roy)
    Analyse van de transcriptionele repressor Kaiso in humane tumoren en tijdens de celcyclus
  247. Denayer Tinneke  (2-Dec-05; F. Van Roy & K. Vleminckx)
    Functional study of the canonical Wnt pathway using transgenic tools in Xenopus laevis
  248. De Craene Bram  (19-may-05; F. Van Roy & G. Berx)
    The role of the Snail family of transcription factors in epithelial-mesenchymal transitions
  249. Van Belle Tom  (25-mar-05; J. Grooten)
    IL-15, a cytokine with direct action on CD8+ T cells, exerts an indirect action on TCR-stimulated CD4+ T cells
  250. Vanden Berghe Tom  (18-feb-05; P. Vandenabeele)
    Molecular interplay between apoptotic and necrotic cell death pathways
  251. Willems An   (28-jan-05; N. Mertens & J. Grooten)
    Tumorafhankelijke T cel activering met bispecifieke antilichamen: optimalisatie door protein-design
  252. Brouckaert Greet  (27-jan-05; P. Vandenabeele)
    Analysis of a cellular model for the recognition and phagocytosis of apoptotic and necrotic cells by macrophages
  253. Lamkanfi Mohamed  (10-nov-04; P. Vandenabeele)
    CARD proteins in apoptosis and inflammation
  254. Reekmans Rieka  (23-sep-04; R. Contreras)
    Transcriptional profiling of the Bax-responsive genes in S. cerevisiae.
  255. Vandenbroucke Klaas  (10-sep-04; E. Remaut, L. Steidler & P. Rottiers)
    Genetically modified Lactococcus lactis as in vivo delivery system for trefoil factors at the intestinal mucosa.
  256. Geysens Steven  (28-jun-04; R. Contreras)
    Klonering en karakterisering van fungale genen betrokken bij eiwit N-glycosylatie, kwaliteitscontrole en secretie.
  257. Vervecken Wouter  (28-jun-04; R. Contreras)
    Modificatie van de N-glycosylatiesyntheseweg van Aspergillus niger en Pichia pastoris.
  258. van Gurp Marjan (25-jun-04; P. Vandenabeele)
    Identification of protein-protein interactions in cell death signalling using the yeast two-hybrid system
  259. Staelens Jan  (31-mrt-04; C Libert)
    A molecular genetic analysis of the TNF resistance of the mouse species Mus spretus
  260. Bogaerts Sven  (13-feb-04; F. Van Roy)
    Characterization of a novel zinc finger protein ANC_2H01 (ZASC1)
  261. Pynaert Gwenda  (21-nov-03; J. Grooten)
    De regulerende werking van macrofagen op luchtweginflammatie in een muismodel voor astma 
  262. Vanpoucke Griet  (26-sep-03; F. Van Roy & G. Berx)
    The human alpha-catenins : regulation mechanisms controlling their expression
  263. Comijn Joke  (26-sep-03; F. Van Roy & G. Berx)
    SIP1-mediated transcriptional regulation of E-cadherin and identification of new SIP1 target genes
  264. Lippens Saskia  (12-sep-03; P. Vandenabeele & W. Declercq)
    Expression, regulation and processing of caspase-14 during epidermal differentiation
  265. Vanhalst Koen  (29-aug-03; F. Van Roy)
    Identification and functional analysis of new cadherin genes, possibly involved in murine brain development
  266. Buys Emmanuel  (23-may-03; P. Brouckaert)
    Target validation od soluble guanylate cyclase using conditional targeted mutagenesis in mice
  267. Carpentier Isabelle  (9-may-03; R. Beyaert)
    Molecular and functional characterization of the tumor necrosis factor receptor associated proteins TRAF1 and TRAF2
  268. Hostens Jeroen  (24-apr-03; P. Brouckaert)
    Onderzoek naar het mechanisme van de versterkende werking van IFN-gamma op het anti-tumoraal effect van TNF
  269. Janssens Sophie  (21-febr-03; R. Beyaert)
    Regulation of Interleukin-1 and endotoxin-induced responses by alternative splicing of MyD88
  270. Van Oekelen Dirk  (28-juni-02; G. Haegeman)
    The 5-HT2 receptor family: atypical regulation and functional insight through altered gene expression using antisense
  271. van Loo Geert  (14-juni-02; P. Vandenabeele)
    Apoptotic and necrotic cell death: cell death domain proteins and release of mitochondrial factors
  272. Strumane Kristin  (14-juni-02; F. Van Roy)
    E-cadherin-dependent differential gene expression in cancer cells reveals the novel E-cadherin-repressed oncogene hECRep1
  273. Callewaert Nico  (31-mei-02; R. Contreras) 
    Protein N-glycosylation : from yeast to man
  274. Vermeulen Linda  (17-mei-02; G. Haegeman)
    Studie van het moleculair mechanisme voor transcriptionele activering van NF- B p65 na inflammatorische stimulatie
  275. Bonné Stefan  (30-apr-02; F. Van Roy)
    Klonering en functionele karakterisering van het desmosomale eiwit plakophiline-3
  276. Janssens Barbara  (29-mrt-02; F. Van Roy)
    Study of two novel members of the human alpha-catenin family
  277. Wielockx Ben  (29-mrt-02; C. Libert & P. Brouckaert)
    De rol van proteasen en de identificatie van genen, coderend voor beschermende eiwitten, in TNF-geïnduceerde hepatitis en letale shock
  278. Hochepied Tino  (21-sep-01; P.Brouckaert & C.Libert)
    Onderzoek naar de rol van acute-fase proteïnen, in het bijzonder alfa1-zuur glycoproteïne, in muismodellen voor lokale en systemische inflammatie
  279. Van Huffel Sofie  (21-sep-01; F. Van Roy & R.Beyaert)
    Identificatie en functionele karakterisering van eiwitten die binden met het zinkvingereiwit A20
  280. Vanhauwe Jurgen  (15-jun-01; G. Haegeman & J. Leysen)
    Karakterisering van de ligand-bindings- en signaaltransductie-eigenschappen van humane dopamine D2- en D3-receptoren
  281. Francken Bart  (17-apr-01; G. Haegeman)
    Heterologous expression of G protein-coupled receptors and reconstituion of G protein coupling : h5-ht5A receptor in mammalian, insect, and bacterial cells
  282. De Wilde Gert  (10-jan-01; G. Haegeman)
    Studie van de ruimtelijke structuur van het TNFR-55 'death domain' en van de stroomafwaartse signalisatie naar MAP-kinasen
  283. Schotte Peter  (15-dec-00; R. Beyaert &F. Van Roy)
    Studie van caspasen en het activeringsmechanismen
  284. Van Craenenbroeck Kathleen  (21-jun-00; G. Haegeman)
    Onderzoek van induceerbare systemen voor heterologene genexpressie in zoogdiercellen
  285. Vanlandschoot Ann  (10-mei-00; F. Van Roy)
    Isolering en karakterisering van catenine- en cadherine-bindende eiwitten met mogelijke functies in signalisatiewegen en genregulatie
  286. Laroy Wouter  (9-mei-00; R. Contreras)
    Structuur-functie analyse van siaalzuur transfererende enzymen
  287. De Bosscher Karolien  (23-mrt-00; G. Haegeman)
    Onderzoek naar het mechanisme van Genrepressie door Glucocorticoïden
  288. Denecker Geertrui  (17-mrt-00; W. Fiers & P. Vandenabeele)
    Role of capases and mitochondria in apoptotic and necrontic cell death
  289. De Backer Marianne  (11-feb-00; R. Contreras)
    Identification of novel molecular targets for drugs against Candida albicans
  290. Dooms Hans  (28-jan-00; J. Grooten &F. Van Roy)
    Differentiële regulatie van apoptose en celdeling door interleukine-2 en -15 tijdens T-lymfocyt-antwoorden